王洪岩，1989年出生，中国水产科学研究院黄海水产研究所助理研究员，2019年获武汉大学生物化学与分子生物学博士学位。主要研究方向：利用基因组学、单细胞转录组学和表观遗传组学等高通量技术手段，聚焦海水养殖物种免疫系统构成和抗病抗逆的分子机制研究，探索免疫系统的功能演化，发掘新的免疫防御机制，并研究免疫与生长和代谢之间的关系。承担国家自然科学基金项目1项，山东省博士后创新项目资助1项。目前在Science Advances，Cell Host & Microbe等杂志发表论文10余篇，其中第一作者2篇。
代表性论文
1. Li W,Wang HY, Zhao X, Duan H, Cheng B, Liu Y, Zhao M, Shu W, Mei Y, Wen Z, Tang M, Guo L, Li G, Chen Q, Liu X, Du HN. A methylation-phosphorylation switch determines Plk1 kinase activity and function in DNA damage repair.Sci Adv. 2019 Mar 6;5(3):eaau7566.
2. Wang HY, Li Y, Xue T, Cheng N, Du HN. Construction of a series of pCS2+ backbone-based Gateway vectors for overexpressing various tagged proteins in vertebrates.Acta Biochim Biophys Sin (Shanghai). 2016 Dec;48(12):1128-1134.
3. Liu X, Huang Y, Tan F,Wang HY, Chen JY, Zhang X, Zhao X, Liu K, Wang Q, Liu S, Piferrer F, Fan G, Shao C. Single-Cell Atlas of the Chinese Tongue Sole (Cynoglossus semilaevis) Ovary Reveals Transcriptional Programs of Oogenesis in Fish.Front Cell Dev Biol. 2022 Mar 1;10:828124.
4. Lu YF, Liu Q, Liu KQ,Wang HY, Li CH, Wang Q, Shao CW. Identification of global alternative splicing and sex-specific splicing via comparative transcriptome analysis of gonads of Chinese tongue sole (Cynoglossus semilaevis).Zool Res. 2022 May 18;43(3):319-330.
5. Lu B, Ren Y, Sun X, Han C,Wang H, Chen Y, Peng Q, Cheng Y, Cheng X, Zhu Q, Li W, Li HL, Du HN, Zhong B, Huang Z. Induction of INKIT by Viral Infection Negatively Regulates Antiviral Responses through Inhibiting Phosphorylation of p65 and IRF3.Cell Host Microbe. 2017 Jul 12;22(1):86-98.e4.
6. Li WZ,Wang HY, Du HN. Research Progress on Non-histone Protein Methylation.Progress in Biochemistry and Biophysics. 2015, 42(11): 1015-1025.
