孙慧慧，工学博士，副研究员，硕士生导师，兼任山东省食品科学技术学会第四届理事。主持包括国家自然科学基金青年基金、中国博士后科学基金、山东省自然科学基金博士基金等在内共计7项课题，并作为科研骨干参与了国家重点研发计划“蓝色粮仓科技创新”重点专项1项。累计发表论文20余篇，其中以第一作者/通讯作者在Comprehensive Reviews in Food Science and Food Safety、Journal of Agricultural and Food Chemistry、International Journal of Biological Macromolecules等领域内权威期刊发表论文12篇；获授权发明专利6项，其中第一发明人4项；参编著作《海洋食品酶工程》1部。荣获神农中华农业科技奖科学研究类成果一等奖（第五完成人，2021）。
主要研究领域为微生物酶与生物催化转化在海洋食品中的应用，主要包括酶的基因发掘和高效表达，催化机制解析和理性分子改造，生化反应过程优化与调控等研究。
代表性论文
[1] H.H. Sun, L. Zhao, X.Z. Mao, R. Cao*, Q. Liu. Identification of a key loop for tuning transglycosylation activity in the substrate-binding region of a chitosanase. Journal of Agricultural and Food Chemistry. 2023, 71, 5585-5591.
[2] N. Cao, G.L. Xia, H.H. Sun*, L. Zhao, R. Cao, H. Jiang, X.Z. Mao, Q. Liu. Characterization of a galactose oxidase from Fusarium odoratissimum and its application in the modifification of agaros. Foods. 2023, 12, 603.
[3] Y.M. Cheng, Z.Y. Li, H.H. Sun*, L. Zhao, Z. Liu, R. Cao, Q. Liu, X.Z. Mao. Immobilization of chitosanase on magnetic nanoparticles: Preparation characterization and properties. Journal of Ocean University of China. 2022, 21, 1381-1388.
[4] 孙慧慧, 杨国淞, 程伊梦, 李昭悦, 赵玲, 曹荣*，刘淇. 海洋寡糖的生物活性研究进展[J]. 食品科学. 2022, 43(13): 276-284.
[5] H.H. Sun, L. Gao, C.H. Xue, X.Z. Mao*. Marine-polysaccharide degrading enzymes: Status and prospects. Comprehensive Reviews in Food Science and Food Safety. 2020, 19, 2767-2796.
[6] H.H. Sun, G.S. Yang, R. Cao*, X.Z. Mao, Q. Liu. Expression and characterization of a novel glycoside hydrolase family 46 chitosanase identified from marine mud metagenome. International Journal of Biological Macromolecules. 2020, 159, 904-910.
[7] H.H. Sun, X.Z. Mao, N. Guo, L. Zhao, R. Cao*, Q. Liu. Discovery and characterization of a novel chitosanase from Paenibacillus dendritiformis by phylogeny-based enzymatic product specificity prediction. Journal of Agricultural and Food Chemistry. 2018, 66, 1139-1145.
[8] H.H. Sun, R. Cao, L.H. Li*, L. Zhao, Q. Liu. Cloning, purification and characterization of a novel GH46 family chitosanase, Csn-CAP, from Staphylococcus capitis. Process Biochemistry. 2018, 75, 146-151.
